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Last-stage refractory Nasopharyngeal cancer, NSCLC Lung cancer, Liver cancer, malignant pleural and peritoneal effusion and pancreatic cancer.
| Case selection： | patients are in advanced and refractory with relapse into cervical lymph node metastasis |
| Usage： | local injection in cervical lymph node |
| Dosage： | oncorine® is intratumoral injected at the dose of 1-3 vials per day, combined with 5-FU (500mg/m2) and cisplatin (20mg/m2). The schedule was continued for 5 days. The cycle was 21 days upto 2~5 cycles. |
Lung cancer:
| Case selection： | Advanced non-small cell lung cancer, CT suggests that there has lesions suitable for injection. |
| Usage： | Intratumoral injection through percutaneous lung puncture with needle guided with B ultrasound or CT |
| Dosage： | Three vials of oncorine® at 1st and 8th day; start with chemotherapy in 4th day; The cycle is 21 days upto to 2～5 cycles. |
Liver cancer:
| Case selection： | Primary or metastatic liver tumor with clinical or phathological diagnosis confirmed. |
| Usage & Dosage： | During operation: regional perfusion or intratumoral injection of residual lesions with dose of 3 vials Intervention procedure: Hepatic artery perfusion with dose of 3 vials. The cycle is 14 days up to 2～5 cycles. Intrahepatic injection: Intratumoral injection through percutaneous and liver puncture guided with B ultrasound and the dose are 3 vials. The cycle is 14 days up to 2～5 cycles. |
Malignant pleural and peritoneal effusions:
| Case selection： | Advanced tumor with malignant pleural and peritoneal effusions |
| Usage： | Pleural and peritoneal perfusion |
| Dosage： | Three vials of oncorine is used at1st and 4th day, and could be combined with local chemotherapy with pleural and peritoneal perfusion. The cycle is 14 days up to 2～5 cycles. |
Pancreatic cancer:
| Case selection： | Incurable pancreatic cancer or recurrence after surgery |
| Usage： | intratumoral injection is guide with EUS |
| Dosage： | Three vials of oncorine combined with gemcitabine（1000mg/m2）Intravenous chemotherapy. The cycle is 28 days up to 2～5 cycles. |