Last-stage refractory Nasopharyngeal cancer, NSCLC Lung cancer, Liver cancer, malignant pleural and peritoneal effusion and pancreatic cancer.
|Case selection：||patients are in advanced and refractory with relapse into cervical lymph node metastasis|
|Usage：||local injection in cervical lymph node|
|Dosage：||oncorine® is intratumoral injected at the dose of 1-3 vials per day, combined with 5-FU (500mg/m2) and cisplatin (20mg/m2). The schedule was continued for 5 days. The cycle was 21 days upto 2~5 cycles.|
|Case selection：||Advanced non-small cell lung cancer, CT suggests that there has lesions suitable for injection.|
|Usage：||Intratumoral injection through percutaneous lung puncture with needle guided with B ultrasound or CT|
|Dosage：||Three vials of oncorine® at 1st and 8th day; start with chemotherapy in 4th day; The cycle is 21 days upto to 2～5 cycles.|
|Case selection：||Primary or metastatic liver tumor with clinical or phathological diagnosis confirmed.|
|Usage & Dosage：||During operation: regional perfusion or intratumoral injection of residual lesions with dose of 3 vials
Intervention procedure: Hepatic artery perfusion with dose of 3 vials. The cycle is 14 days up to 2～5 cycles.
Intrahepatic injection: Intratumoral injection through percutaneous and liver puncture guided with B ultrasound and the dose are 3 vials. The cycle is 14 days up to 2～5 cycles.
Malignant pleural and peritoneal effusions:
|Case selection：||Advanced tumor with malignant pleural and peritoneal effusions|
|Usage：||Pleural and peritoneal perfusion|
|Dosage：||Three vials of oncorine is used at1st and 4th day, and could be combined with local chemotherapy with pleural and peritoneal perfusion. The cycle is 14 days up to 2～5 cycles.|
|Case selection：||Incurable pancreatic cancer or recurrence after surgery|
|Usage：||intratumoral injection is guide with EUS|
|Dosage：||Three vials of oncorine combined with gemcitabine（1000mg/m2）Intravenous chemotherapy. The cycle is 28 days up to 2～5 cycles.|