(2) Cell Therapies Associated With Carcinoma

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Associated Therapies


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Shenzhen SiBiono GeneTech

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Therapy Approach

Head and neck squamous cell carcinoma (HNSCC)

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Head and neck squamous cell carcinoma (HNSCC)

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  • United States

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  • PMDA Approved

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Therapy Name: Gendicine

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Sunway Biotech Co. Ltd

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Therapy Approach

Last-stage refractory Nasopharyngeal cancer, NSCLC Lung cancer, Liver cancer,

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Last-stage refractory Nasopharyngeal cancer, NSCLC Lung cancer, Liver cancer, malignant pleural and peritoneal effusion and pancreatic cancer.

 

Case selection: patients are in advanced and refractory with relapse into cervical lymph node metastasis
Usage: local injection in cervical lymph node
Dosage: oncorine® is intratumoral injected at the dose of 1-3 vials per day, combined with 5-FU (500mg/m2) and cisplatin (20mg/m2). The schedule was continued for 5 days. The cycle was 21 days upto 2~5 cycles.

Lung cancer:

Case selection: Advanced non-small cell lung cancer, CT suggests that there has lesions suitable for injection.
Usage: Intratumoral injection through percutaneous lung puncture with needle guided with B ultrasound or CT
Dosage: Three vials of oncorine® at 1st and 8th day; start with chemotherapy in 4th day; The cycle is 21 days upto to 2~5 cycles.

Liver cancer:

Case selection: Primary or metastatic liver tumor with clinical or phathological diagnosis confirmed.
Usage & Dosage: During operation: regional perfusion or intratumoral injection of residual lesions with dose of 3 vials
Intervention procedure: Hepatic artery perfusion with dose of 3 vials. The cycle is 14 days up to 2~5 cycles.
Intrahepatic injection: Intratumoral injection through percutaneous and liver puncture guided with B ultrasound and the dose are 3 vials. The cycle is 14 days up to 2~5 cycles.

Malignant pleural and peritoneal effusions:

Case selection: Advanced tumor with malignant pleural and peritoneal effusions
Usage: Pleural and peritoneal perfusion
Dosage: Three vials of oncorine is used at1st and 4th day, and could be combined with local chemotherapy with pleural and peritoneal perfusion. The cycle is 14 days up to 2~5 cycles.

Pancreatic cancer:

Case selection: Incurable pancreatic cancer or recurrence after surgery
Usage: intratumoral injection is guide with EUS
Dosage: Three vials of oncorine combined with gemcitabine(1000mg/m2)Intravenous chemotherapy. The cycle is 28 days up to 2~5 cycles.

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Therapy Name: Oncorine

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